Effects of different fats on blood cholesterol levels
| Fatty Acid |
VLDL |
LDL |
HDL |
Comments |
| Saturated fat |
|
|
|
|
| Lauric (12:0) |
No effect |
Increase |
Increase |
|
| Myristic Acid (14:0) |
No effect |
Appreciable increase |
Increase |
|
| Palmitic (16:0) |
No effect |
Appreciable increase |
|
|
| Stearic (18:0) |
No effect |
No effect |
No effect |
|
| Cis-Monounstaured fat |
|
|
|
|
| Oleic (18:1cis) |
No effect |
Decrease |
Increase |
|
| Trans-Monunsaturated fat |
|
|
|
|
| Elaidic (18:1trans) |
No effect |
Appreciable increase |
Decrease |
|
| Polyunsaturated fat (w 6) |
|
|
|
|
| Linoleic (18:2 n-6) |
No effect |
Appreciable decrease |
(*Increase) |
*HDL may decrease if n-6 is >10% of total energy |
| Polyunsaturated fat (w 3) |
|
|
|
|
| a -linolenic (18:3 n-3) |
Appreciable decrease |
May decrease |
(*Decrease) |
*increase in LDL if initial LDL is high*decrease in HDL is fed in large quantities |
| Eicosapentaenoic (20:5 n-3) |
Appreciable decrease |
|
(*Decrease) |
*increase in LDL if initial LDL is high*decrease in HDL is fed in large quantities |
| Docosahexaenoic (22:6 n-3) |
Appreciable decrease |
|
(*Decrease) |
*increase in LDL if initial LDL is high*decrease in HDL is fed in large quantities |
N.B. The omega3 fatty acids, Eicosapentaenoic and Docosahexaenoic may help reduce risk of heart disease due to their anti-arrhythmic effect. Metabolic studies suggest that omega-3 fatty acids may prevent platelet aggregation, reduce inflammation and improve arterial compliance.
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